TPO gene rs2071400 polymorphisms as an independent risk factor for hypothyroidism in Iraqi patients

RETN Gene Polymorphisms as Risk Factor in Diabetic Patients with Covid-19 Infection

People with diabetes mellitus (DM) represent a population group that is at high risk of developing a poor prognosis for COVID-19. Having diabetes increases the risk of serious illness, ICU stay, and death from COVID-19. The current study included 150 participants with diabetes, 100 patients of whom had COVID-19 (46 male, 54 female), and 50 had diabetes only (28 male, 22 female), aged between 37...

Screening of LEP gene polymorphisms as a risk factor for obesity and type 2 diabetes in Iraqis

The prevalence of obesity and diabetes changes dramatically with lifestyle and unequal risk among individuals have made scientists interested to understand how the environment interferes with genetic factors to make it so-called genetic predisposition. This study aimed to explore wherethe most variable region is in leptin gene and analyse  microsatellite repeats with direct sequencing in Iraqis...

CYP1A1 gene polymorphisms as a risk factor for pterygium

PURPOSE Both cytochrome P4501A1 (CYP1A1) and glutathione S-transferase M1 (GSTM1) have been demonstrated to be involved in the metabolism of polycyclic aromatic hydrocarbons (PAHs). BaP 7,8-diol 9,10-epoxide (BPDE), an ultimate metabolite of benzo(a)pyrene (BaP), attacks deoxyguanosine to form a BPDE-N2-dG adduct resulting in p53 gene mutations. Our previous report indicated that BPDE-like DNA ...

obesity as an independent risk factor for the development of microalbuminuria

Lipoprotein lipase gene polymorphisms as risk factors for stroke: a computational and meta-analysis

Objective(s): Stroke is the most common neurological disorder and genetic susceptibility has an important role in its etiology. Polymorphism in several genes such as lipoprotein lipase (LPL) is propounded as a risk for stroke. This meta-analysis investigated the association of rs285 and rs320 LPL polymorphism with stroke risk. Materials and Methods: We searched PubMed, Clarivate Analytics Web o...